ORGLIST: brine/water washing

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From: Ohad Ilovich (ilovicho$##$gmail.com)
Date: Thu Nov 27 2008 - 06:09:41 EST


Dear all,
I have a rather strange question. I've seen in a couple of articles where
someone extracted his compound in some organic solvent and than washed the
organic phase in both brine and water.
As i understand it brine is used when the organic solvent is miscible with
water and the salting out effect of the brine inhibits the compound
dissolved in the organic phase from passing to the brine. water is used
pretty much of all other solvents.
The only idea why brine AND water will be used is to maybe get rid of any
NaCl leftover which may have passed to the organic phase.
Am i mistaken or is this double washing just a waste of time?

-- 
Ohad Ilovich, M.Sc, B.Pharm
Cyclotron/Radiochemistry Unit
Nuclear Medicine Department
Hadassah/Hebrew University Hospital
Jerusalem 91120,  Israel
Fax : 972 2 6412033
Tel: 972 2 6777197

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