Re: ORGLIST: Molecular Sieve

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From: Ilya Avrutov (IAvrutov$##$dalton.com)
Date: Wed Nov 26 2008 - 08:45:49 EST


Hello Mohd,
 
By no means you need to crush the sieves: they will loose their potency
completely. For anhydrous conditions you are supposed the sieves 3A or
4A. But be sure they will not be crushed during stirring.
 
Best,
Ilya Avrutov
 
Ilya Avrutov, PhD
Process Development Team Leader
Dalton Pharma Services
349 Wildcat Rd., Toronto, ON
M3J 2S3 Canada

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From: everybody-bounces$##$orglist.net
[mailto:everybody-bounces$##$orglist.net] On Behalf Of mohd zulkefeli
Sent: Wednesday, November 26, 2008 2:46 AM
To: everybody$##$orglist.net
Subject: ORGLIST: Molecular Sieve

Dear Colleagues,
 
I would like to seek opinion on using molecular sieve during anhydrous
reaction. Which one is more effective, using the molecular sieve in its
original shape or crush it to the powder shape?
 
Thank you very much.
 
M. Zulkefeli

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