ORGLIST: selective N-acylation

Date view Thread view Subject view Author view Attachment view

From: Mugunthan G (mugunthan_gee$##$yahoo.co.in)
Date: Tue Nov 20 2007 - 11:29:26 EST


hi Joyti,
               To the best of my knowledge, there is no method for exclusive N-acylation. but i can suggest a possible solution to your problem. just do a complete acylation of L-glucosamine, then treat it with sodium methoxide in methanol, it will deprotect only O-acetyl group leaving the amide bond of N-acetyl as such, then just add, H+ resin to neutralise , filter and concentrate, u will get N-acetyl-L-glucosamine
  regards
  mugunthan

everybody-request$##$orglist.net wrote:
  Send Everybody mailing list submissions to
everybody$##$orglist.net

To subscribe or unsubscribe via the World Wide Web, visit
http://two.pairlist.net/mailman/listinfo/everybody
or, via email, send a message with subject or body 'help' to
everybody-request$##$orglist.net

You can reach the person managing the list at
everybody-owner$##$orglist.net

When replying, please edit your Subject line so it is more specific
than "Re: Contents of Everybody digest..."

Today's Topics:

1. (no subject) (Jyoti Agarwal)

----------------------------------------------------------------------

Message: 1
Date: Mon, 19 Nov 2007 18:35:05 +0530
From: "Jyoti Agarwal"
Subject: ORGLIST: (no subject)
To: everybody$##$orglist.net
Message-ID:
<29dc46070711190505w74b81b0fk86dc490fcb7d5517$##$mail.gmail.com>
Content-Type: text/plain; charset=ISO-8859-1

I want to know the procedure for the selective acetylation of NH2
group in L-glucosamine in presence of OH group. if there is any
reference regarding to this please send to me.
Thanks in advance.

------------------------------

_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address

End of Everybody Digest, Vol 40, Issue 3
****************************************

MUGUNTHAN.G
DEPARTMENT OF MEDICINAL CHEMISTRY
NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH
SECTOR-67,PHASE-10, MOHALI
PUNJAB-160062
INDIA

       
---------------------------------
 Find a mall, hotel or ATM in any part of India. Click here.


_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address


Date view Thread view Subject view Author view Attachment view

This archive was generated by hypermail 2.1.4 : Thu Feb 18 2010 - 16:51:51 EST