ORGLIST: removal of DMF

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From: Mugunthan G (mugunthan_gee$##$yahoo.co.in)
Date: Tue Jun 26 2007 - 02:46:08 EDT


hi,
         its not that difficult to remove DMF , we do it routinely using Buchi rotaevaporator at 2mbar and 5 C cooling temp, it goes well. i used to evaporate 250 ml in 5-7 hr. also DMF forms azeotrope with toluene, which boils at low temp, u can try this.

MUGUNTHAN.G
DEPARTMENT OF MEDICINAL CHEMISTRY
NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND REASEARCH
SECTOR-67,PHASE-10, MOHALI
PUNJAB-160062
INDIA
 
       
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