ORGLIST: How to make this reaction work?

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From: Peng Gao (pgao00$##$st.lzu.edu.cn)
Date: Fri Jun 01 2007 - 11:54:30 EDT


Dear all,
   I did some reactions about alkynyllithium and lactone addition ( please see the
attachment), but they all didn¡¯t work. I try to add alkynyllithium to lactone
slowly and add lactone substrate to the alkynyllithium THF solution in a portion,
all the reactions didn¡¯t work. I also try to add BF3.Et2O to the reaction, the
reaction din¡¯t work all the same. I don¡¯t know why, any one can give me some
suggestion and some papers about this kind of addition? Thank you in advance.

   Yours,
    Peng Gao




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