Re: ORGLIST: TLC help - monitoring a reaction

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From: Sachin Chaphekar (purvi_chaphekar$##$yahoo.com)
Date: Mon Feb 05 2007 - 00:55:59 EST

Hi! TLC should not be a problem, since MMA is not that volatile. I had a look in other suggestions you got, treating with KMnO4 sounds a very good idea. However in my experience instead of dipping TLC in soln. spray the KMnO4 over TLC the spots appear more distinct this way. Also if everything else fails what you can also do is check your reacn mass sample by a dilute bromine solution. MMA will decolourise bromine solution (bromine is added on the double bond of MMA), in absence or low concentrations it will not. But be careful about the quantity of bromine soln. you will use. Sachin ----- Original Message ---- From: Ken Knott <esprcorn$##$hotmail.com> To: everybody$##$orglist.net Sent: Friday, February 2, 2007 10:46:09 AM Subject: ORGLIST: TLC help - monitoring a reaction Ok, easy one again for ya guys... Again, I'm a 1st year grad student so I'm still struggling with some of the basics... I'm running a reaction where I'm supposed to monitor the disappearance of the starting material (methyl methacrylate) by TLC. I'm using a reaction scheme/protocol from another paper. But methy methacrylate appears to be very limitedly UV active and very volatile. So I can't really see the spot and even if I could it evaporates before it can elute. I think... Before realizing this I tried monitoring on GC in the lab, but I didn't get anything.. Again, likely due to the volatility of methyl methacrylate.... Is there another way I can monitor the consumption of the methyl methacrylate? Or will I have to settle for monitoring the product possibly? Or just give it 24 hours and work it up crossing my fingers? In the paper where I got the reaction, their substrates are all UV active and non-volatile so this was not an issue for them. This is fun stuff... but I'm stumped... Thanks!! Ken _________________________________________________________________ Get in the mood for Valentine's Day. View photos, recipes and more on your Live.com page. http://www.live.com/?addTemplate=ValentinesDay&ocid=T001MSN30A0701 _______________________________________________ ORGLIST - Organic Chemistry Mailing List Website / Archive / FAQ: http://www.orglist.net To post a message (TO EVERYBODY) send to everybody$##$orglist.net To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address ____________________________________________________________________________________ No need to miss a message. Get email on-the-go with Yahoo! Mail for Mobile. Get started. http://mobile.yahoo.com/mail


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