From: THT (medichemtang$##$263.net)
Date: Wed Nov 22 2006 - 14:58:01 EST
Hi Kamal:
Mabye NaH(2 mol) as base, ans THF(add some HPMT) as solvent is work.
----- Original Message -----
From: Kamal Morendha
To: everybody$##$orglist.net
Sent: Wednesday, November 22, 2006 7:27 PM
Subject: ORGLIST: Alkylation with Ph-Et-Br
Hi !
I'm doing one alkylation reaction involving N-Ethoxycarbonylmethyl-L-Valine & 2-Phenylethyl Bromide as under :
EtOOC-CH2-NHCH-CH(CH3)2-COOH + 2-PhCH2CH2Br -------> EtOOC-CH(CH2CH2Ph)-NHCH-CH(CH3)2-COOH
I tried using K2CO3 in diff. solvents, Na-EtOH, but could not get the conversion at all.
May I get some suggetions for this Alkylation ?
Thanks,
Kamal
---------------------------------------------------------------------------------------------
"If you don't have hope, you'll not get what is beyond your hope."
It has been notified to the sender that you have read this message.
--------------------------------------------------------------------------------
_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
This archive was generated by hypermail 2.1.4 : Thu Feb 18 2010 - 16:48:30 EST