Re: ORGLIST: hi

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From: hai zhang (haizhang67$##$yahoo.com)
Date: Fri Nov 10 2006 - 17:49:26 EST

Babu, Try CCl4 as solvent, if not soluble, try CF3Ph as solvent. NBS/AIBN as bromonation reagents, heat the mixture to 60oC to intitiate radical reaction. " Radical bromination of benzylic position. The alkyl substituted aromatic system was dissolved into CCl4 with AIBN (0.2 equiv.) and NBS (1.5 equiv.). The mixture was heated to 65oC for 4 hours. The resulting mixture was diluted with ethyl acetate, and washed with brine. The organic layer was dried and concentrated. The residue was separated by silica gel column to give product with 70% of yield. CF3Ph could be used to replace CCl4 for higher temperature. " From www.ecompound.com Good luck! Hai ----- Original Message ---- From: Kishore Babu Ch <kbchilukuri$##$yahoo.com> To: everybody$##$orglist.net Sent: Thursday, November 9, 2006 2:05:58 AM Subject: ORGLIST: hi hi everybody if any body suggest how to prepare bromination on 4-propyl pyridine i.e at CH2 position.i try with NBS and Bromine .but reaction not proceeded at cooling and RT and reflux temp under DCM condition bye ch.kishsore babu ____________________________________________________________________________________ Sponsored Link Mortgage rates near 39yr lows. $420k for $1,399/mo. Calculate new payment! http://www.LowerMyBills.com/lre _______________________________________________ ORGLIST - Organic Chemistry Mailing List Website / Archive / FAQ: http://www.orglist.net To post a message (TO EVERYBODY) send to everybody$##$orglist.net To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address


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