From: Nandan Vakatkar (nandan2000$##$yahoo.com)
Date: Sat Oct 07 2006 - 14:13:13 EDT
Hey Diogo,
Well, you can prepared from resorcinol by Vilsmeier formylation or Reimer-Tiemann phenol formylation.
Regards.
NandanV. Vakatkar
Research Fellow
Institute of Chemical Technology
Mumbai, India.
Hi everybody!
I´m in need of synthetising 2,4-dihydroxybenzaldehyde since we can´t buy
it. Is there any metodology you can suggest? thanks
Diogo
------------------------------
Message: 2
Date: Tue, 3 Oct 2006 12:25:18 -0700 (PDT)
From: Sengen Sun
Subject: ORGLIST: selective hydrogenation
To: everybody$##$orglist.net
Message-ID: <20061003192519.43224.qmail$##$web53707.mail.yahoo.com>
Content-Type: text/plain; charset=iso-8859-1
It is very hard indeed. In similarly cases, I always
reduce azido group with triethylphosphine in
MeCN/water = 9:1, rt, O/N. It is an easy reaction,
even although the cost is some higher in the large
scale than hydrogenation.
Sengen
--- Jeff Li wrote:
> Does any one know how to hydrogenate an azido group
> without affecting the benzyloxy group in a
> molecule?
>
> I've tried using Pd-C in the solvent of EtOAc, but
> it seemed that it was not really easy to control on
> a large scale.
>
> I'll appreciate for your advice.
>
>
> ---------------------------------
> ÇÀ×¢ÑÅ»¢Ãâ·ÑÓÊÏä-3.5GÈÝÁ¿£¬20M¸½¼þ£¡ >
_______________________________________________
> ORGLIST - Organic Chemistry Mailing List
> Website / Archive / FAQ: http://www.orglist.net
> To post a message (TO EVERYBODY) send to
> everybody$##$orglist.net
> To unsubscribe, send to
> everybody-request$##$orglist.net the message:
> unsubscribe your_orglist_password your_address
__________________________________________________
Do You Yahoo!?
Tired of spam? Yahoo! Mail has the best spam protection around
http://mail.yahoo.com
------------------------------
Message: 3
Date: Wed, 4 Oct 2006 06:24:28 +0100 (BST)
From: Mugunthan G
Subject: ORGLIST: reduction of azide
To: everybody$##$orglist.net
Message-ID: <20061004052428.8309.qmail$##$web8901.mail.in.yahoo.com>
Content-Type: text/plain; charset="iso-8859-1"
hi,
u can very well reduce azide to amine in presence of other groups like benzyl or benzyloxy, by using triphenylphosphine in water.
MUGUNTHAN.G
DEPARTMENT OF MEDICINAL CHEMISTRY
NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND REASEARCH
SECTOR-67,PHASE-10, MOHALI
PUNJAB-160062
INDIA
---------------------------------
Find out what India is talking about on - Yahoo! Answers India
Send FREE SMS to your friend's mobile from Yahoo! Messenger Version 8. Get it NOW
-------------- next part --------------
An HTML attachment was scrubbed...
URL: http://two.pairlist.net/pipermail/everybody/attachments/20061004/33537830/attachment-0001.htm
------------------------------
Message: 4
Date: Wed, 4 Oct 2006 13:33:46 +0200
From: "Ohad Ilovich"
Subject: Re: ORGLIST: reduction of azide
To: "Mugunthan G" ,
Message-ID: <003001c6e7a8$f46883d0$0e33a8c0$##$CYCLO14>
Content-Type: text/plain; charset="iso-8859-1"
Hi,
Would this work as well for reducing a nitro group to amine in the presance of a benzyl or benzyloxy?
----- Original Message -----
From: Mugunthan G
To: everybody$##$orglist.net
Sent: Wednesday, October 04, 2006 7:24 AM
Subject: ORGLIST: reduction of azide
hi,
u can very well reduce azide to amine in presence of other groups like benzyl or benzyloxy, by using triphenylphosphine in water.
MUGUNTHAN.G
DEPARTMENT OF MEDICINAL CHEMISTRY
NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND REASEARCH
SECTOR-67,PHASE-10, MOHALI
PUNJAB-160062
INDIA
------------------------------------------------------------------------------
Find out what India is talking about on - Yahoo! Answers India
Send FREE SMS to your friend's mobile from Yahoo! Messenger Version 8. Get it NOW
------------------------------------------------------------------------------
_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
************************************************************************************
This footnote confirms that this email message has been scanned by
PineApp Mail-SeCure for the presence of malicious code, vandals & computer viruses.
************************************************************************************
-------------- next part --------------
An HTML attachment was scrubbed...
URL: http://two.pairlist.net/pipermail/everybody/attachments/20061004/da8b4715/attachment-0001.html
------------------------------
Message: 5
Date: Wed, 4 Oct 2006 05:27:32 -0700 (PDT)
From: hai zhang
Subject: Re: ORGLIST: selective hydrogenation
To: Sengen Sun , everybody$##$orglist.net
Message-ID: <20061004122732.71259.qmail$##$web54408.mail.yahoo.com>
Content-Type: text/plain; charset="iso-8859-1"
It is called:
Staudinger (Hermann Staudinger 1881 - 1965 Nobel Prize Chemistry 1953 ) Azide reduction is a very useful way to make primary amine from azide. A very important transformation in Med. Chem. Another mechanism is the formation of 4-membered ring, and then it decomposes.
www.ecompound.com
Hai
Sengen Sun wrote:
It is very hard indeed. In similarly cases, I always
reduce azido group with triethylphosphine in
MeCN/water = 9:1, rt, O/N. It is an easy reaction,
even although the cost is some higher in the large
scale than hydrogenation.
Sengen
--- Jeff Li wrote:
> Does any one know how to hydrogenate an azido group
> without affecting the benzyloxy group in a
> molecule?
>
> I've tried using Pd-C in the solvent of EtOAc, but
> it seemed that it was not really easy to control on
> a large scale.
>
> I'll appreciate for your advice.
>
>
> ---------------------------------
> ÇÀ×¢ÑÅ»¢Ãâ·ÑÓÊÏä-3.5GÈÝÁ¿£¬20M¸½¼þ£¡ >
_______________________________________________
> ORGLIST - Organic Chemistry Mailing List
> Website / Archive / FAQ: http://www.orglist.net
> To post a message (TO EVERYBODY) send to
> everybody$##$orglist.net
> To unsubscribe, send to
> everybody-request$##$orglist.net the message:
> unsubscribe your_orglist_password your_address
__________________________________________________
Do You Yahoo!?
Tired of spam? Yahoo! Mail has the best spam protection around
http://mail.yahoo.com
_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
---------------------------------
Want to be your own boss? Learn how on Yahoo! Small Business.
-------------- next part --------------
An HTML attachment was scrubbed...
URL: http://two.pairlist.net/pipermail/everybody/attachments/20061004/f944de7e/attachment.htm
------------------------------
_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
End of Everybody Digest, Vol 26, Issue 2
****************************************
---------------------------------
The all-new Yahoo! Mail goes wherever you go - free your email address from your Internet provider.
_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
This archive was generated by hypermail 2.1.4 : Tue Feb 13 2007 - 14:17:01 EST