RE: ORGLIST: knoevenagal condesation

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From: Richard Prankerd (Richard.Prankerd$##$vcp.monash.edu.au)
Date: Tue Jun 06 2006 - 20:05:55 EDT

Ani:
 
The Knoevenagel condensation is described in the following reviews:
 
Jones G, Organic Reactions, vol. 15, 204-, (1967)
Cope AC, JACS, 59, 2327-30 (1937)
House HO, Modern Synthetic Reactions, 2nd Ed., Benajmin, Menlo Park, CA
(1972), Ch. 10
Prout FS, J Org Chem, 18, 928-933 (1953)
 
A modification to the original Knoevenagel reaction that I found useful
for ketones that do not condense under the normal conditions is given
by:
 
Lehnert W, Tetrahedron 29, 635-7 (1973)
 
Rgds
Richard
 
Richard J. Prankerd, PhD
Senior Lecturer
Victorian College of Pharmacy, Monash University
381 Royal Pde., Parkville VIC 3052

Phone: INT+613-9903-9003
Phax: INT+613-9903-9583

Drugs need to be designed with delivery components in mind - Takeru
Higuchi

-----Original Message-----
From: everybody-bounces$##$orglist.net
[mailto:everybody-bounces$##$orglist.net] On Behalf Of Anil Saini
Sent: Tuesday, 6 June 2006 5:06 PM
To: everybody
Subject: ORGLIST: knoevenagal condesation

Hello all, I am looking for a paper but no where getting , can any one
help. This is in concern with knoevenagal condesation of aldehyde with
malonic acid.
thanx in advance
Ani

 


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