From: rren$##$wesleyan.edu
Date: Sun Apr 23 2006 - 23:51:57 EDT
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chemistry/synthesis in this website: AnswerASAP.com, who answer questions
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> Dear all
> i`m trying a series of reactions to convert hydroxy to amine on a
> pyrrolidine derivative but the amine should be with retention of
> configuration . If i will use normal mesylation followed by
> azidation then amine it gives inverted product. I tried mitsonobu
> with methyl tosylate on hydroxy to get inverted mesyl but reaction
> didn`t go.
> Any suggestions from you all
>
> Thanks in advance
>
> Ashwani Sharma
>
>
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