From: will jones (willjones46$##$hotmail.com)
Date: Sat Jul 16 2005 - 05:04:11 EDT
Hi again guys
I asked everyone for advice regarding synthesising the monoactivated ester
of DTPA. I said that the only solvent I could find to dissolve DTPA in was
DMSO. My coupling procedure used DCC/NHS.
I know that DMSO in the presence of DCC is an oxidising agent. This wouldnt
be a problem, except that the DCC will react with DMSO, and also I am
preparing the activated ester in situ to then react with an alcohol bearing
Would DMSO react with HBTU? Could I therefore substitute DCC for HBTU? That
way my reaction would be faster as well.
So, in short, can I use HBTU in DMSO, without the DMSO reacting with HBTU?
Thanks in advance
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
List coordinator: Joao Aires de Sousa (coordinator$##$orglist.net)
This archive was generated by hypermail 2.1.4 : Thu Feb 18 2010 - 16:58:09 EST