ORGLIST: acylations of polyols with acyloyl chloride

Date view Thread view Subject view Author view Attachment view

From: cardman (cardman400$##$
Date: Thu Mar 03 2005 - 19:22:37 EST

I want to react a polyol with acryloyl chloride. I'm
afraid of running the reaction neat b/c of
polymerization. The polyol won't dissolve in any
aprotic solvents except for pyridine, DMF or DMSO.
Pyridine seems like it will just give me a mess. DMSO
will be very difficult to remove. Can I run this
reaction in DMF? I found only a single example on the
web. Don't acid chlorides react with DMF to form a
different acylating agent?

I've also seen an example of an esterification using
an acid chloride run in aqueous bicarbonate. I have
always wondered why this works. Why doesn't the acid
chloride just hydrolyze?



Celebrate Yahoo!'s 10th Birthday!
Yahoo! Netrospective: 100 Moments of the Web
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ:
To post a message (TO EVERYBODY) send to everybody$##$
To unsubscribe, send to everybody-request$##$ the message: unsubscribe your_orglist_password your_address
List coordinator: Joao Aires de Sousa (coordinator$##$

Date view Thread view Subject view Author view Attachment view

This archive was generated by hypermail 2.1.4 : Thu Feb 18 2010 - 16:58:09 EST