ORGLIST:Synthesis of naphthil

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From: Potter, Phil (Phil.Potter$##$stjude.org)
Date: Sat Sep 13 2003 - 10:20:23 EDT


Hi,

I am trying to synthesize naphthil via the condensation of 2-napthaldehyde using thiamine/NaOH/EtOH (cf benzil). Does anyone have any experience with this condensation, and if so, what yields have been obtained. Whilst I see apparent product by TLC, the yield seems very low (10-15%).

Thanks,

Phil Potter
phil.potter$##$stjude.org

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