ORGLIST:Lederer-Manasse Condensation

Date view Thread view Subject view Author view Attachment view

From: fmohr$##$uwo.ca
Date: Fri May 30 2003 - 08:05:44 EDT

My group is having problems with a seemingly simple reaction:
The condensation of bromal with phenol to give Br3CCH(C6H4OH)2. The synthesis
of this coumpound is described in the patent literature, however we have not
been able to reproduce the preparation. Instead of a "colourless solid" we
have consistently obtained a dark purple resinous gum, which proved to be a
horrible mess acording to HNMR. We have tried varying solvents, time,
temperature and acid catalyst but with no sucess.
Has anyone here got any advice or "magic tricks" to get this reaction to work
propperly or any other suggestions on how to get to this compound?
Many thanks to the online organic chemistry community!
F. Mohr
Canada 

-- 

_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
List coordinator: Joao Aires de Sousa (coordinator$##$orglist.net)
Date view Thread view Subject view Author view Attachment view

This archive was generated by hypermail 2.1.4 : Fri Sep 19 2003 - 12:17:26 EDT