Re: ORGLIST:cleavage of amine-borane complex

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From: Yuehui Zhou (yuehuizhou$##$hotmail.com)
Date: Thu May 08 2003 - 23:15:23 EDT


You may try to heat your stuff with short chain alkylamines and dry them under vacuum. Borane will form complex with both amines (one is your product). But he one with short alkylamine will be evaporated.

 

Y. Zhou

>From: "Research Scholars,tpr"
>To: everybody@orglist.net
>Subject: ORGLIST:cleavage of amine-borane complex
>Date: Thu, 8 May 2003 12:13:05 +0800 (SGT)
>
>Dear all
> i tried reducing one longchain(c18) secondary amide with NaBH4/I2.
>the reaction went through properly and i got the amine-borane complex, but
>when i tried to cleave this with peroxide it went in some other way and i
>could not get the final secondary amine( in the IR spectra the
>corresponding peak for the amine-borane complex is disappeared) . can you
>suggest me a definite way to cleave this kind of amine- borane complexes(
>longchain).
>
>thank you in advance
>
>M. SHARATH CHANDRA
>
>*******************************************************************************
>Research Scholar Email:tprscrs@
>Prof. T.P.Radhakrishnan's Group uohyd.ernet.in
>Theoretical & Material's Chemistry Group Tel:(040)-23011068
>School of Chemistry (040)-23010500
>University of Hyderabad extn: 4827 & 4750
>Hyderabad-500 046 FAX:91-40-23012460
>India
>*******************************************************************************
>
>
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