ORGLIST:how to suppress side reaction?

Date view Thread view Subject view Author view Attachment view

From: peter walla (peter.walla$##$post.sk)
Date: Thu Feb 27 2003 - 12:59:42 EST

Hi Dear Everybody!
Please, could you someone tell me, how to supress the side reaction- formation of biphenyl (from phenylzinkiumchloride), when the reactant is 1-chloro-4-nitro-benzene and phenylzinkiumchloride (prepared from phenylmagnesiumchloride and zinc chloride) under 5 mol% Pd(PPh3)4 as catalyst in refluxing THF for 2 hours. The products are 4-nitrobiphenyl and biphenyl, but i dont want to separate it by mean of chromatography, because of similar Rf factors. Would addition of LiCl into the reaction mixture help to supress formation of biphenyl? Or what should I add there? I want to do just with palladium catalyst, and not with nickel. Or, please, how should I find this information in web, or scifinder or beilstein commander?
I appreciate any advice, ít is very important to me.
Thank you!
Peter

________
Chcete umiestnit svoju stranku na Internet?: http://www.postweb.sk
_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
List coordinator: Joao Aires de Sousa (coordinator$##$orglist.net)

Date view Thread view Subject view Author view Attachment view

This archive was generated by hypermail 2.1.4 : Fri Sep 19 2003 - 12:17:25 EDT