From: JSM (jaininder2002$##$yahoo.com)
Date: Mon Sep 02 2002 - 05:30:51 EDT
I wish to Dehydroxylate an organic compound.The
conventional methods used to do this are rather harsh,
detrimental to other functional groups in the
molecule,
involve expensive reagents and difficult conditions.
I have theoretically come up with a possible method.
I want the following : R-OH -> R-H
This is how I have proposed the method / steps :
R-OH + HBr(48% sol) -> R-Br + H2O ....1
R-Br + Zn (powder) -> R-ZnBr ....2
R-ZnBr + H2O(Dil acid)->R-H + ZnBrOH..3
(Note: R contains an ester group)
Compare to GRIGNARD reaction :
R-MgI + H2O -> R-H + MgI(OH).
The above is used to destroy excess Grignard reagent.
It cannot be used in reactions where there is an ESTER
group,as the R-MgI will react with it.
Please tell me if my Steps 1-3 above are feasible,and
any precautions, drawbacks associated with it.Thanks,
My e-mail : jaininder2002$##$yahoo.com
__________________________________________________
Do You Yahoo!?
Yahoo! Finance - Get real-time stock quotes
http://finance.yahoo.com
_______________________________________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net
To post a message (TO EVERYBODY) send to everybody$##$orglist.net
To unsubscribe, send to everybody-request$##$orglist.net the message: unsubscribe your_orglist_password your_address
List coordinator: Joao Aires de Sousa (coordinator$##$orglist.net)
This archive was generated by hypermail 2.1.4 : Fri Sep 19 2003 - 12:16:54 EDT