ORGLIST: Re: Indinavir

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From: G.P.Moss (G.P.Moss$##$qmw.ac.uk)
Date: Wed Nov 08 2000 - 06:45:41 EST


While it is correct to suggest there are 32 stereoisomers of indinavir the
drug is defined as the one stereoisomer. In case anyone wants to know what
the structure of indinavir is (the names of intermediates I and II were
not correct) it is (2R,4S)-2-benzyl-5-[(2S)-2-tert-butylcabamoyl)-4-(3-
pyridylmethyl)piperazin-1-yl]-4-hydroxy-N-[(1S,2R)-2-hydroxyindan-1-yl]-
pentanamide.

Gerry Moss
_________________________________________________________________________

Dr GP Moss Telephone: +44 20 7882 3262
Department of Chemistry
Queen Mary & Westfield College Facsimile: +44 20 7882 7794
Mile End Road
London E1 4NS, United Kingdom E-mail: g.p.moss$##$qmw.ac.uk

IUPAC chemical nomenclature data base: http://www.chem.qmw.ac.uk/iupac/
IUBMB biochemical nomenclature data base: http://www.chem.qmw.ac.uk/iubmb/

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