From: Jacob Zabicky (zabicky$##$bgumail.bgu.ac.il)
Date: Wed Nov 01 2000 - 05:17:40 EST
Dear Pedro,
Data from CRC Handbook.
TEA pKa 11.01 at 18 C
I have no data on DMAP: N,N-(dimethylamino)pyridine, but you are still
missing something! the placement of the dimethylamino group. It makes quite
a difference. Your problem compound should no have a pKa value very
different from the following ones:
2-aminopyridine pKa 6.82 at 20 C (add about 0.8)
4-methylaminopyridine pKa 9.65 at 20 C (add about 0.5)
If the group is at position 3 the pKa should not differ much from that at
position 4.
Saludos,
Jacob
At 8:49 1/11/0, Pedro Merino wrote:
>The pKa values that Chris Borella asked for are:
>
>DMAP: N,N-(dimethylamino)pyridine
>TEA: triethylamine
>
>Look at the Prof. Evans' group web page:
>http://daeiris.harvard.edu/DavidEvans.html
>
>*****************************************
>Dr. Pedro Merino
>Laboratorio de Sintesis Asimetrica
>Departamento de Quimica Organica
>Facultad de Ciencias
>Edificio D. Planta 3. QO3545
>Plza. San Francisco, s/n
>E-50009 Zaragoza (Spain)
>
>Phone: +34 976 762075
>Fax: +34 976 762075
>E-mail: pmerino$##$posta.unizar.es
>URL (group): http://wzar.unizar.es/acad/fac/cie/quiorg/asimetrica/mtm.html
>URL(personal):
>http://wzar.unizar.es/acad/fac/cie/quiorg/asimetrica/staff/merino.html
>
>
>
>
>
>
>> -----Mensaje original-----
>> De: owner-orglist$##$dq.fct.unl.pt [mailto:owner-orglist$##$dq.fct.unl.pt]En
>> nombre de Jacob Zabicky
>> Enviado el: miercoles, 01 de noviembre de 2000 8:31
>> Para: Multiple recipients of list orglist
>> Asunto: Re: ORGLIST: pKa's
>>
>>
>> Hello Chris,
>>
>> pKa of what?
>>
>> Jacob
>>
>> At 10:08 31/10/0, Chris Borella wrote:
>> >Hello,
>> >I am looking for pka values for DMAP and TEA any help would be greatly
>> >appreciated.
>> >
>> >-chris
>> >
>> ><!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
>> ><HTML><HEAD>
>> ><META http-equiv=Content-Type content="text/html; charset=iso-8859-1">
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>> ><BODY bgColor=#ffffff>
>> ><DIV><FONT face=Arial size=2>Hello,</FONT></DIV>
>> ><DIV><FONT face=Arial size=2>I am looking for pka values for
>> DMAP and TEA any
>> >help would be greatly appreciated.</FONT></DIV>
>> ><DIV><FONT face=Arial size=2></FONT> </DIV>
>> ><DIV><FONT face=Arial size=2>-chris </FONT></DIV></BODY></HTML>
>>
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Institutes for Applied Research Fax. 972-7-6472969
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