From: César Barbero (cbarbero$##$exa.unrc.edu.ar)
Date: Wed Sep 27 2000 - 09:21:55 EDT
Dear people,
I'm trying to protect a secondary amino(diphenylamine) group in a
molecule using the formation of an amide. The protection step (reaction
with 10% acetic anhidride in acetic acid and a drop of concentrated
sulfuric acid) works very well but after the intended reaction we are
unable to hydrolize the amide. We hace tried with 10 % KOH in water and
ethanol, 10% sulfuric and HCl, CO3K2 in CH3OH, t-ButO- in tButOH
without sucess. Any suggestions? (other than to change the protecting
group).
Thank you in advance
Dr. Cesar Barbero
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