Re: ORGLIST: amine chromatography

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From: Eva Horn Moeller (ehorn$##$medchem.dfh.dk)
Date: Tue May 30 2000 - 06:21:10 EDT

For the quite difficult polyamines, eluent mixtures such as
dichloromethane - methanol - isopropylamine (e.g. 4:4:1) has been
employed for silica gel chromatography. TEA would probably work fine,
too. These compounds can also be purified using reverse phase-HPLC, with
eluent mixture as e.g. 15% aq. MeCN + 0.1% trifluoroacetic acid. You may
of course try this with a usual column using reverse phase silica gel.
Best regards,
Eva Horn Moeller
(MSc, PhD)

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