From: Madhavan Sridharan (madhavan.sridharan$##$bioconindia.com)
Date: Mon Dec 06 1999 - 23:24:11 EST
Zinc borohydride is not commercially available. I have worked on this and
have papers published in Syn Comm and JOC.
It is easily prepared in the lab by dissolving a freshly fused ZnCl2 in THF
(care has to be taken, since this is highly exothermic) and adding 2
equivalents of NaBH4. Upon stirring at room temperature for about 12h the
conversion is complete.
The resulting solution has been successfully used for reduction of
acids, (JOC, 1995, 60, 5314)
amino acids, synthetic communications, 26, 703, 1996
and for hydroboration, unpublished results, Ald. Acta, 31, 1998.
Addition of metal salts to NaBH4 results in the formation of insitu metal
borohydrides, in the case of CoCl2, insitu formation of Co(BH4)2 in
solution results which serves as a better reducing agent.
Madhavan
__________________
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net/
List coordinator: Joao Aires de Sousa (jas$##$mail.fct.unl.pt)
This archive was generated by hypermail 2.1.4 : Fri Sep 19 2003 - 12:15:34 EDT