Re: ORGLIST: zinc borohydride/comment

From: Robyn L Crumbie (R.Crumbie$##$uws.edu.au)
Date: Sun Apr 09 2000 - 19:42:17 EDT

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>You might be able to generate it in situ, eg substrate + ZnCl2 in methanol,
>add NaBH4 with stirring. I know this works for CoCl2/NaBH4 for reducing
>nitriles, nitros and amides, see Tet Lett. no. 52 p4555 1969
>
>Paul Handley
>Dept. of Chemistry
>University of Queensland
>Brisbane, Australia
>__________________

I used this procedure a number of years ago. The only difference was that I
generated the Zn(BH4)2 FIRST, then added the substrate.

Dr Robyn L Crumbie FRACI

Department of Chemistry, UWS Macarthur
PO Box 555
Campbelltown 2560
AUSTRALIA

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