ORGLIST: Basicity

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From: Jonas Nilsson (jonni$##$ifm.liu.se)
Date: Fri Feb 25 2000 - 03:34:43 EST

Dear List Members

What would you thing about the basicity of a function like this?

R-CO-NH-CH2-(p-Ph)-C(-NH2 <-this)=N-CO-CH2-Ph

I thought it would be allmost non basic but my HPLC-runs says otherwise.
The Z-group makes it non-nuclephilic (i think) but maybe not non-basic?

Anyone have an opinion
/jN 

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