Good afternoon everyone: We have been working on the Corey-Itsuno reduction with aromatic ketones using borane-THF complex, and have noticed that the borane reagents when obtained from different vendors sometimes gives different ee's when all other conditions are equal. Has anyone else had this problem? We would greatly appreciate any insights that anyone may have. Thanks in advance Timothy L. McAllister timothy.mcallister@spcorp.com Schering Plough Research Institute ____________________________________________________________________________ ___ > __________________ > > ORGLIST - Organic Chemistry Mailing List > Website and Archive: http://www.orglist.net/ > List coordinator: Joao Aires de Sousa (jas@mail.fct.unl.pt) __________________ ORGLIST - Organic Chemistry Mailing List Website and Archive: http://www.orglist.net/ List coordinator: Joao Aires de Sousa (jas@mail.fct.unl.pt) __________________ ORGLIST - Organic Chemistry Mailing List Website and Archive: http://www.orglist.net/ List coordinator: Joao Aires de Sousa (jas@mail.fct.unl.pt)