ORGLIST: 16- amino hexaddecanamide

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From: Dr. T.P. Radhakrishanan-(RS) (tprscrs$##$uohyd.ernet.in)
Date: Sat Sep 25 1999 - 21:15:04 EDT


hi there!
         can anybody suggest me the method of convering 16-hydroxy
hexadecanoic acid into 16-amino hexadecamide. we are converting the acid
to acid chloride and then planning to do ammonia rex for getting the amide
but for that we need to protect the hydroxy from making the lactone with
the acid chloride. is there any protacting group which can protect the
hydroxy group during the acid chloride formation and at the same time in
the next ammonia rex. we get ammide from acid cholide and amine from
protecated OH group so tha tfinnally we end up with 16-amino
hexadecanamide.

 thanks a lot.

sonika


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