Re: ORGLIST: deuterium exchange

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From: John Deutsch (deutschj$##$essex.UCHSC.edu)
Date: Mon Apr 26 1999 - 16:28:21 EDT


I have a simple question, and I'm wondering if someone can answer it or
refer me to a source.

Does acetonitrile have labile hydrogens which can exchange with
hydroxides?
For instance- can ACN + CH3-OD make CH3-OH? I am observing something
like this, but am unclear if it is due to water in the ACN or from ACN
itself. The extent is greater than I would expect if it were from the
trace amount of water which contaminates the ACN


John Deutsch
University of CO HSC

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