From: by way of Joao Aires de
Sousa (r.ragno$##$caspur.it)
Date: Tue Mar 18 1997 - 02:50:13 EST
Dear colleagues,
I've synthesized many 6-substituted-2-alkylthio-4-oxo-pyrimidines by
S-alkylation of 2-thiouracils with alkyl halides and potassium carbonate
in DMF, but when I tried to introduce the cyclopropyl group in the same
way (i.e. with cyclopropyl iodide) I failed. Do you have any suggestion?
I'll summarize to the list the answers I'll get.
Thank you in advance,
Gianluca " Blue Merlin" Sbardella
***************************************************************
* *
* Dr. Gianluca Sbardella E-mail: r.ragno$##$caspur.it *
* Dip. Studi Farmaceutici *
* Universita' "La Sapienza" Phone: 39-6-49913814 *
* P.le A. Moro, 5 Fax: 39-6-491491 *
* 00185 Roma *
* ITALY *
* *
* *
* "Il destino e' quel che e', non c'e' scampo piu' per me.." *
* (Gene Wilder, "Frankenstein Junior") *
* *
* "Destiny, destiny, no escaping that for me..." *
* (Gene Wilder, "Young Frankenstein") *
* *
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